Tired muscles aching joints or stubborn nerve pain can interrupt even the simplest parts of your day. With so many creams gels sprays and supplements promising relief it is easy to wonder which ones actually make a difference. Some focus on fast cooling while others lean on natural ingredients or targeted support for nerves and muscles. Pain relief does not have a single answer. Each solution brings something different to the table. Curious which options might work for your needs or routine? Take a closer look and see how different approaches stack up when it comes to comfort and convenience.
Table of Contents
Neuropasil
At a Glance
Neuropasil delivers a focused, fast-acting topical approach for nerve, muscle, and joint pain using natural ingredients like aloe, urea, and menthol. The formula is built to provide quick, targeted relief during flare-ups, and the brand supports purchase flexibility with single packs, bundles, and promotions. For people who prefer drug-free, topical options for conditions such as sciatica, neuropathy, or arthritis, Neuropasil presents a clear, conversion-focused shopping experience. Its combination of rapid relief and natural actives makes it a standout for daily symptom management.
Core Features
Neuropasil offers a fast-acting formula formulated with natural ingredients including aloe, urea, and menthol to soothe nerve and muscle discomfort. Key features include targeted topical relief for nerve pain and muscles, multiple pack sizes with bundle discounts, a money-back guarantee, and free shipping offers. Neuropasil.com is an e-commerce website dedicated to providing targeted topical pain relief solutions primarily for nerve, muscle, and joint pain. Its core function is to promote and sell a line of fast-acting creams formulated with natural ingredients like aloe, urea, and menthol. The website emphasizes quick pain alleviation for conditions such as sciatica, neuropathy, arthritis, and muscle soreness, positioning itself as a drug-free alternative to traditional medications. It features product pages with options for single packs and bundles, alongside promotional offers including discounts and free shipping. The site also offers educational content through blogs and guides on various pain conditions, aimed at informing consumers about pain management. Its layout incorporates user-friendly navigation for purchasing, along with customer service contact details, policy links, and social media links. The primary focus is on conversion, encouraging visitors to buy pain relief products through direct calls to action and attractive deals.
Pros
- Natural ingredients: The formula relies on aloe, urea, and menthol, which provide soothing, familiar actives for topical relief without systemic medication.
- Fast relief effectiveness: The product is designed to act quickly on localized pain, making it useful during acute flare-ups or after activity.
- Multiple bundle options for savings: Neuropasil offers single packs and bundled choices so you can lower per-unit cost when you commit to ongoing relief.
- Dedicated solutions for nerve and muscle pain: The product is focused specifically on nerve, muscle, and joint complaints rather than being a general-purpose topical.
- Provides targeted topical relief: The cream is applied directly to problem areas, enabling localized effect and minimizing systemic exposure.
Cons
- Limited product range mentioned: Neuropasil is intentionally focused on creams for nerve and muscle relief, which may be a design choice to concentrate on efficacy rather than offering many product lines.
- Pricing may be higher compared to some OTC options: The pricing reflects a formulated, targeted solution and bundle discounts, which is a trade-off for specialized, natural ingredients.
- Availability limited to online purchase (based on provided info): Neuropasil’s e-commerce-first model prioritizes direct-to-consumer benefits like promotions and free shipping, but it means in-store pickup isn’t described.
Who It’s For
Neuropasil is best for individuals seeking natural, fast-acting topical relief for nerve and muscle pain—particularly people with chronic conditions like neuropathy, sciatica, or arthritis and active individuals who need quick, localized relief after strain or activity.
Unique Value Proposition
Neuropasil’s strength lies in combining a targeted, fast-acting topical formula with natural actives and an e-commerce experience optimized for conversion and convenience. The focus on nerve-specific relief—paired with money-back guarantees, bundle savings, and free shipping—positions Neuropasil as a superior choice for users who want a trusted, drug-free option tailored to chronic and activity-related pain. Its educational content and user-friendly purchase flow further reduce friction, helping you understand when and how to use the product and encouraging consistent, effective management of symptoms.
Real World Use Case
A person with chronic nerve pain applies Neuropasil cream during a flare-up, massaging it into the painful area for rapid, soothing relief. The natural ingredients calm irritation and the targeted approach helps restore function without oral medication.
Pricing
From $29.99 USD for a 4 oz cream, with bundle options available for savings.
Website: https://neuropasil.com
Biofreeze
At a Glance
Biofreeze is a long-standing topical pain-relief line built around a menthol-based cooling formula designed to target sore muscles and joints. It’s marketed to athletes and active people and has multiple formats—gels, sprays, creams, and patches—so you can choose the application that fits your routine. Fast-acting and intended to last up to eight hours in many formulations, Biofreeze aims for targeted, drug-free relief rather than systemic treatment.
Core Features
Biofreeze delivers cooling relief through a menthol-based formula that focuses on localized muscle and joint discomfort. The brand offers several application methods—gel, spray, cream, and patch—so you can apply it before training, after activity, or for ongoing soreness. Key claims include fast onset of cooling sensation and long-lasting relief of up to eight hours, plus mess-free options like sprays and patches for easier use during busy days.
Pros
- Trusted brand history: With more than 30 years of presence, Biofreeze benefits from a long track record that builds consumer trust.
- Effective targeted relief: The menthol-based formula is designed to deliver a clear cooling sensation that helps mask pain at the application site.
- Multiple formats available: You can choose gels, sprays, creams, or patches depending on whether you want portability, precision, or a mess-free option.
- Fast-acting with durable effect: Many users expect quick relief and the brand states relief can last up to eight hours, which suits daily use and recovery routines.
- Suitable for various musculoskeletal complaints: The product line is positioned for athletes, active individuals, and those with muscle or joint soreness from different causes.
Cons
- Menthol can irritate sensitive skin: The same cooling ingredient that provides relief may cause stinging, burning, or irritation for people with sensitive or compromised skin.
- Some formulations may feel greasy or sticky: Certain creams or gel bases can leave a residue that some users find unpleasant.
- Limited transparency in ingredient detail on some pages: The product data notes gaps in comprehensive ingredient and safety information for every formulation, which can make cautious users hesitate.
Who It’s For
Biofreeze is aimed at active people and athletes who need fast, localized relief and prefer topical, drug-free options. It’s also useful for caregivers and physical therapists looking for a temporary, targeted cooling approach for clients with muscle soreness, strains, or joint discomfort. If you have sensitive skin, approach with caution and test a small area first.
Unique Value Proposition
Biofreeze stands out by combining a widely recognized menthol cooling formula with a range of application formats so users can match the product to their lifestyle. Its long market presence and emphasis on targeted, non-systemic relief make it a straightforward option for those who want quick, on-the-spot pain control without oral medication.
Real World Use Case
A professional athlete might apply Biofreeze gel after an intense training session to reduce localized muscle soreness before sleep, then use a patch on a persistent knee area during a tournament weekend for hands-off, extended cooling relief.
Pricing
Pricing varies depending on the product format and the retailer; specific prices are not listed on the product page.
Website: https://biofreeze.com
Hempvana
At a Glance
Hempvana is a U.S.-based line of hemp seed oil topical pain relievers that targets joint, muscle, arthritis, and nerve pain with natural formulations. The brand emphasizes fast relief and positions its products as a safer option for users with blood pressure concerns compared to some oral painkillers. You’ll find a variety of formats—creams, gels, and roll-ons—plus subscription options for ongoing use. While Hempvana’s natural focus and shipping perks are appealing, detailed ingredient transparency is limited in the provided information.
Core Features
Hempvana offers hemp seed oil–based topical products formulated for fast pain relief across multiple formats, including creams, gels, and roll-ons to match personal preference and application needs. The brand supports regular use through subscription and auto-delivery options and markets its products as an alternative that may be safer for customers worried about blood pressure impacts from oral medications. Free shipping and bundle discounts are noted as part of the overall buying experience.
Pros
- Wide product range from a U.S.-based company: Hempvana offers several delivery formats so you can choose the one that fits your routine, whether a quick roll-on or a massageable cream.
- Focus on fast pain relief: The formulations are marketed specifically for quick symptom relief of joint, muscle, arthritis, and nerve pain, which can help users seeking rapid, topical results.
- Natural ingredients emphasis: The products center on hemp seed oil and botanical components, appealing to people who prefer plant-based, topical options.
- Subscription savings and convenience: Auto-delivery options make it easy to maintain a steady supply and often reduce per-unit costs.
- Free shipping available: Shipping incentives lower overall cost and simplify ordering for regular users.
Cons
- Limited ingredient detail in provided content: The available information doesn’t list full ingredient panels, which makes it harder to evaluate potential allergens or exact active concentrations.
- Price variability and potential subscription cost: Prices span a wide range and subscription pricing can sometimes increase total spend depending on the product selected.
- Limited retail presence indicated: Based on the supplied data, Hempvana appears marketed mainly through its website, which may restrict in-person trial opportunities.
Who It’s For
Hempvana suits people seeking natural, topical relief for chronic or acute pain—those dealing with knee, back, joint, or nerve discomfort who prefer plant-based formulations. It’s also a fit for users concerned about blood pressure interactions with oral painkillers and for anyone who values subscription convenience and free shipping to maintain regular treatment.
Unique Value Proposition
Hempvana’s unique offering is a hemp seed oil–centered lineup positioned as a fast-acting, topical alternative to oral pain medications, combined with subscription convenience and free shipping to support continuous use. The focus on natural botanicals and messaging around blood pressure safety differentiates it within topical pain relief options.
Real World Use Case
A customer with chronic arthritis applies Hempvana’s arthritis gel daily and enrolls in auto-delivery to ensure they never run out. The roll-on or cream format lets them target sore joints quickly after activity, while bundle discounts and free shipping reduce their long-term cost.
Pricing
Starting at $17.99; prices range up to approximately $99.99 depending on product and purchase options, with discounts available for subscriptions and bundles.
Website: https://hempvana.com
Nerve Renew
At a Glance
Nerve Renew is a doctor-endorsed supplement aimed at supporting nerve health and reducing discomfort through a proprietary blend of science-backed ingredients. It targets nerve blood flow, myelin support, and nerve fiber density to improve nerve communication. Users report meaningful improvements, but results vary and the product requires ongoing use to maintain benefits.
Core Features
Nerve Renew combines a proprietary blend of 10 ingredients designed to support blood flow to nerves, regenerate nerve tissue, and rebuild the myelin sheath that insulates nerve fibers. Key components listed in the formula include stabilized R-Alpha Lipoic Acid, Methylcobalamin (Vitamin B12), and Benfotiamine (Vitamin B1), along with other vitamins and herbs focused on increasing nerve fiber density and protecting nerves from further sensitivity.
Pros
- Scientifically formulated with proven ingredients: The formula highlights ingredients that are commonly studied for nerve support, which suggests a research-based approach to formulation.
- Supports nerve regeneration and protection: The product claims to help rebuild myelin and increase nerve fiber density, positioning it as a targeted option for nerve repair.
- Customer success stories indicating significant relief: Reported user experiences include reduced discomfort and improved mobility, which can be meaningful for people struggling with persistent nerve symptoms.
- No automatic shipments for single orders: You can purchase a single supply without being locked into recurring deliveries, which gives buyers control over their commitment.
- Backed by a 1-year satisfaction guarantee: A year-long guarantee reduces purchase risk and shows the company’s confidence in the product.
Cons
- Results may vary from person to person: Individual responses to supplements differ, so outcomes are not guaranteed for everyone.
- Requires regular intake for best results: The product’s benefits rely on consistent daily use, which may be inconvenient or costly over time.
- Higher doses and proprietary blends may be costly for some: Ongoing use and the structure of multi-month bundles could be expensive for people on tight budgets.
Who It’s For
Nerve Renew is aimed at individuals experiencing nerve discomfort such as tingling, numbness, weakness, or chronic nerve pain—especially those affected by aging, diabetes, or past nerve injuries. If you want a targeted, supplement-based approach to support nerve function and are willing to use a product consistently, this may be a reasonable option to try.
Unique Value Proposition
Nerve Renew positions itself as a clinician-endorsed, multi-ingredient supplement specifically formulated to address nerve blood flow, myelin repair, and nerve fiber density. Its combination of stabilized active compounds and a one-year satisfaction guarantee seeks to differentiate it from single-ingredient options and generic multivitamins.
Real World Use Case
A typical real-world scenario is someone with chronic numbness and disrupted sleep due to nerve discomfort who takes Nerve Renew daily and, over weeks to months, notices improved mobility, less nighttime discomfort, and better rest—outcomes that can translate into more activity and a higher quality of life.
Pricing
Starting at $69 for a 1-month supply; $147 for a 3-month supply (saving $60), and a free starter bottle option available with subscription.
Website: https://nerverenew.com
nervive
At a Glance
nervive positions itself as a focused nerve health brand offering supplements and educational content for people with nerve discomfort, aches, or weakness. The site emphasizes quick-acting claims for some products and also offers sleep-support items tied to nerve health. If you want a company centered on nerve care and learning more about nerve issues, nervive presents a clear, specialized option — but you’ll need to dig deeper on the site for full product specifics and pricing.
Core Features
nervive’s core offerings are nerve-focused supplements designed to support nerve health and provide relief from nerve-related symptoms. The product lineup, as presented, highlights items that claim measurable results in about 14 days, plus formulations aimed at improving sleep where nerve issues interfere with rest. The website also acts as an educational hub with articles explaining nerve function, common problems, and the science the brand cites to back its approach.
Pros
- Dedicated nerve health focus: nervive centers its products and content on nerve care, which creates a specialized resource for people with nerve pain or neuropathy concerns.
- Educational resources available: The site provides articles and information to help you learn about nerve function and potential causes of nerve discomfort.
- Claims of quick results: Some products are presented with claims of noticeable effects in about 14 days, which can be appealing when you want faster relief.
- Attention to joint and nerve awareness: The homepage emphasizes awareness and education, which may help you make more informed choices about managing nerve issues.
- Perceived market leadership: The site describes nervive as a recognized brand in nerve care, lending it credibility in this niche.
Cons
- Limited product detail on the homepage: The homepage does not provide full ingredient lists, dosing guidance, or clinical evidence, so you must explore further to evaluate efficacy and safety.
- Availability and specifics unclear: Pricing, package sizes, and exact product formulations are not specified on the main page, making purchase planning difficult.
- Requires extra browsing to assess range and results: To confirm which product fits your needs and whether claims are substantiated, additional browsing or customer support contact is necessary.
Who It’s For
nervive is best for people experiencing nerve discomfort, numbness, tingling, or weakness who want a brand dedicated to nerve health and educational support. It also suits caregivers or active people who prefer targeted supplements and want a starting point to learn about nerve-related sleep issues.
Unique Value Proposition
nervive’s unique value lies in its single-minded focus on nerve care: it combines product offerings with educational content so you can both try targeted supplements and learn the rationale behind them. That blend of commerce and education helps you make a more informed decision about nerve-support strategies.
Real World Use Case
Imagine you’ve started experiencing persistent tingling and poor sleep due to nerve irritation. You explore nervive, read their articles to understand possible causes, and try a nerve-support supplement that promises improvement in about 14 days while monitoring sleep-focused products to restore rest.
Pricing
Not specified on the homepage. Likely varies by product.
Website: https://nervivehealth.com
Stopain
At a Glance
Stopain is a topical pain reliever formulated to deliver fast, targeted cooling relief for arthritis, back pain, and muscle soreness. It contains a relatively high 8% menthol concentration and combines glucosamine, eucalyptus, and peppermint oil to enhance the soothing effect. Available as a gel, roll-on, or spray and made in the USA, Stopain positions itself as a drug-free alternative for localized pain without oral medication side effects. Overall, it’s a straightforward, potent option if you want quick cooling relief applied directly where it hurts.
Core Features
Stopain’s core strengths are its ingredient profile and application versatility. The product uses 8% menthol, which provides a strong cooling sensation that acts as a counterirritant to interrupt pain signals. Formulation also includes glucosamine and essential oils such as eucalyptus and peppermint, which may contribute to comfort and a pleasant aroma. The product comes in three formats—gel, roll-on, and spray—so you can choose the delivery method that fits your routine and the affected area. The manufacturer states the formula provides immediate and lasting relief for muscle aches, joint pain, and arthritis.
Pros
- Fast-acting and penetrating relief: The 8% menthol concentration is designed to provide a rapid cooling sensation that many users identify as immediate relief.
- Targeted and versatile application methods: Gel, roll-on, and spray formats let you apply Stopain precisely where you need it, whether a small joint or a broad muscle group.
- High menthol concentration for effective relief: At 8% menthol, the product offers a stronger cooling effect than lower-concentration topicals.
- Made in the USA with quality ingredients: Being manufactured domestically may reassure buyers about production standards.
- HSA/FSA eligible: Eligibility for health spending accounts can make the product more affordable for some users.
Cons
- Incomplete formulation transparency: Specific formulation details beyond the listed ingredients aren’t fully provided, so results may vary and it’s harder to compare to other topicals.
- Risk of allergic reactions: Ingredients like menthol, eucalyptus, and peppermint oil can cause irritation or allergic reactions in sensitive individuals.
- Pricing not disclosed on site: The website does not list prices directly, so you must contact the retailer or visit the site to get cost information.
Who It’s For
Stopain is best for people who prefer topical, drug-free approaches to manage localized pain—especially those with arthritis, post-workout muscle soreness, or recurring back aches. If you want a product that works quickly, can be applied on the go, and is covered by HSA/FSA, Stopain fits that profile. It’s less suitable for those with known sensitivities to menthol or essential oils.
Unique Value Proposition
Stopain’s unique value lies in combining a high menthol percentage with multiple delivery formats and supplemental ingredients like glucosamine, all made in the USA. That mix gives users a strong, flexible topical option for immediate, localized cooling relief without relying on oral medications.
Real World Use Case
After a tough workout, you can spritz or apply Stopain to sore hamstrings or shoulders to get a quick cooling sensation that helps you continue your day with less discomfort. The roll-on or gel works well for targeted spots like knees or wrists.
Pricing
Pricing not explicitly provided on the website. Please visit the site or contact retailer for detailed pricing information.
Website: https://stopain.com
KRT Athletic Muscle Cream
At a Glance
KRT Athletic Muscle Cream is a topical solution aimed at fast relief from muscle cramps and fatigue using transdermal nutrition technology. It’s positioned for athletes and trainers who need localized, rapid action to treat cramps during performance or recovery. The cream promises quick absorption and targeted relief, but availability and limited long-term data are notable drawbacks.
Core Features
KRT pairs a topical analgesic with transdermal nutrition technology designed to deliver chemical energy at the cellular level where applied. Key capabilities include rapid absorption, localized action at the site of cramping, and a stated focus on increasing muscle endurance and performance. The formula is intended to relieve muscle fatigue and cramps quickly and is presented as an aid for both treatment and prevention of sports-related muscle issues.
Pros
- Provides rapid relief from cramps and muscle fatigue: The formulation and rapid absorption are designed to act quickly at the site of discomfort, helping users get back to activity sooner.
- Effective at the site of application: Localized action means relief is concentrated where you apply the cream rather than generalized across the body.
- Used and recommended by athletic trainers and athletes: The product’s positioning highlights real-world use in sporting environments, suggesting practitioner trust in its short-term effects.
- Easy to apply: As a topical cream, application is straightforward and can be performed quickly during breaks or between training sessions.
- Helps prevent muscle injuries during sports: By addressing cramps and fatigue proactively, the cream is marketed as part of injury-prevention routines for active users.
Cons
- Currently backordered and unavailable for immediate purchase: The product’s lack of current availability may frustrate users who need immediate relief or routine access.
- Price may be a consideration for some users: The listed regular price could be a barrier for budget-conscious consumers, especially if repeated use is required.
- Limited information on long-term effects: There is sparse data on extended use or long-term outcomes, which may concern users seeking sustained treatment strategies.
Who It’s For
This cream is ideal for athletes, fitness enthusiasts, athletic trainers, and individuals who experience acute muscle cramps or fatigue and need a fast, localized solution. If you compete, train frequently, or work in roles that require rapid muscle recovery, this product is positioned to support short-term performance and recovery needs.
Unique Value Proposition
KRT’s unique selling point is its transdermal nutrition technology combined with a topical analgesic to deliver localized cellular support and rapid relief. It emphasizes both immediate symptom control and a concept of supporting muscle energy where cramps occur, making it distinct from generic topical pain relievers focused only on surface-level cooling or heating.
Real World Use Case
Certified trainers reportedly use the cream at sporting events to manage players’ muscle cramps mid-game, allowing athletes to return to play within minutes. This practical application highlights its role as an on-the-spot, performance-focused remedy for acute muscle issues.
Pricing
Regular price $15.98 — currently unavailable (backordered).
Website: https://krtrelief.com
Pain Relief Solutions Comparison
This table provides a comprehensive overview of different pain relief products, their key features, pros, cons, pricing, and ideal user profiles, helping you to make an informed decision.
Product | Key Features | Pros | Cons | Pricing |
---|---|---|---|---|
Neuropasil | Fast-acting topical pain relief with natural ingredients like aloe, urea, and menthol. Available in single packs and bundles with a focus on nerve, muscle, and joint pain. | Natural ingredients, fast relief, bundle options, targeted relief | Limited product range, higher pricing compared to some OTC options, online availability only | From $29.99 (4 oz cream) |
Biofreeze | Menthol-based formula offering up to eight hours of relief. Available in gels, sprays, creams, and patches for muscle and joint pain. | Trusted brand, effective relief, multiple formats, long-lasting effect | Menthol can irritate sensitive skin, some formulations may feel greasy or sticky, limited ingredient transparency | Varies by product format |
Hempvana | Hemp seed oil–based topicals for joint, muscle, arthritis, and nerve pain. Supports subscription for regular use with an emphasis on natural ingredients. | Wide product range, fast relief, natural ingredients, subscription savings | Limited ingredient transparency, price variability, limited retail presence | From $17.99 to $99.99 |
Nerve Renew | Supplement designed to support nerve health using a blend of ingredients like R-Alpha Lipoic Acid and Methylcobalamin for nerve regeneration. | Scientifically formulated, supports regeneration, no auto shipments, backed by a 1-year guarantee | Results vary, requires regular intake, may be costly for long-term use | $69 (1-month), $147 (3-month) |
nervive | Supplements targeting nerve health with educational support. Claims of quick results in about 14 days. | Dedicated nerve focus, educational resources, quick results | Limited product detail on homepage, unclear availability/pricing, requires extra browsing for specifics | Pricing not specified |
Stopain | High 8% menthol concentration with glucosamine and essential oils in gel, roll-on, or spray. Immediate cooling relief for arthritis and muscle pain. | Fast-acting, versatile application, high menthol concentration, made in USA, HSA/FSA eligible | Incomplete formulation transparency, risk of allergic reactions, pricing not disclosed | Pricing not explicitly provided |
KRT Athletic | Transdermal nutrition for rapid relief from cramps using topical cream. Designed for athletes with quick absorption and focused on muscle fatigue prevention. | Rapid relief, localized action, trusted by trainers, easy application, helps prevent injuries | Currently backordered, price consideration, limited long-term use info | $15.98 (currently backordered) |
Note: Pricing and availability are subject to change; refer to product websites for current details.
Fast Relief for Nerve and Muscle Pain: Experience the Neuropasil Difference
If you are reading the “Best menthol Products – Expert Comparison 2025” article, you probably know the struggle of finding pain relief that actually lasts. You want a solution that works quickly, targets nerve, muscle, and joint flare-ups, and uses trusted ingredients like menthol. Too often, generic creams miss the mark on stubborn pain from sciatica, neuropathy, arthritis, or overuse injuries. That repeated discomfort can make everyday life feel overwhelming. Imagine a new kind of relief—one designed for those who need results they can really feel and trust.
Now is the time to regain comfort and control with Neuropasil’s targeted menthol pain relief. Our fast-acting creams combine menthol, aloe, and urea for natural, drug-free relief that goes where you need it most. Choose from flexible single packs or value bundles and enjoy discounts and free shipping. Ready to move with more freedom and less pain? Visit https://neuropasil.com to start your journey to daily comfort.
Frequently Asked Questions
What are the key benefits of using menthol products for pain relief?
Menthol products provide a cooling sensation that can help mask pain and reduce discomfort in localized areas. They are fast-acting and often offer relief for sore muscles, joint pain, and sports injuries without the need for systemic medications.
How do I choose the right menthol product for muscle soreness?
When selecting a menthol product for muscle soreness, consider the formulation type (gel, cream, spray, or patch) based on your convenience and the affected area. Higher menthol concentrations can provide stronger cooling effects, while ease of application may vary by product format.
Can menthol products be used for nerve pain relief?
Yes, many menthol products are formulated to target nerve pain as they provide localized cooling relief that can soothe irritation or discomfort. Always consult product guidelines and take precautions, especially if you have sensitive skin.
Are there any side effects associated with menthol topical products?
While menthol products are generally safe, they can cause skin irritation, stinging, or allergic reactions in sensitive individuals. It’s advisable to conduct a patch test before widespread use and remove the product if any adverse effects occur.